Fig. 5.

Peptides of CD151-triggered active immunity enhanced the CD8 cell infiltration and reduced MDSC. (a) MDSCs from ICR and BABL/c mice blood were double stained with anti-mouse Gr-1-APC and CD11b-PerCP and analyzed with FCM (n = 6/group). (b) The H22 primary tumour and 4T1 lung metastases were harvested at the end of experiments and stained with HE and anti-mouse CD8 (pictured at 200 ×) (n = 6/group). Infiltration of CD8⁺ T cell in tumour microenvironment was calculated. Results are representative of two independent experiments. P-values were determined by two-tailed Student's t-test (*, P<0.05; **, P < 0.01; ***, P <0.001).