Table 2.
Frequency of single-nucleotide polymorphism genotypes with hepatitis C virus infection
| Genotypes | HCV RNA | Total, n (%) | OR (95% CI) | |
|---|---|---|---|---|
| Negative, n (%) | Positive, n (%) | |||
| rs12979860 (IL-28B) | ||||
| CC | 58 (89.2) | 7 (10.8) | 65 (43.6) | 0.89 (0.29–2.75) |
| CT | 59 (86.8) | 9 (13.2) | 68 (45.6) | 1.39 (0.46–4.27) |
| TT | 15 (93.8) | 1 (16.2) | 16 (10.8) | 0.49 (0.02–3.96) |
| rs2228145 (IL-6 receptor) | ||||
| AA | 67 (90.5) | 7 (9.5) | 74 (49.7) | 0.68 (0.22–2.09) |
| AC | 46 (86.8) | 7 (13.2) | 53 (35.6) | 1.31 (0.42–4.06) |
| CC | 19 (86.4) | 3 (13.6) | 22 (14.7) | 1.27 (0.26–5.41) |
| rs1800795 (IL-6 promoter) | ||||
| GG | 97 (88.2) | 13 (11.8) | 110 (73.8) | 1.17 (0.33–4.59) |
| GC | 32 (88.9) | 4 (11.1) | 36 (24.2) | 0.96 (0.24–3.49) |
| CC | 3 (100) | 0 | 3 (2.0) | 0.00 (0.0–15.87) |
HCV – Hepatitis C virus; IL – Interleukin; OR – Odds ratio; CI – Confidence interval