Table 2.

Factor correlation with PHQ-9 changes

	Univariable		Multivariable
	PHQ-9 mean difference (95% CI)	p-value	PHQ-9 mean difference (95% CI)	p-value
Age	− 0.05 (− 0.01 to 0.008)	0.096		NS
Sex (male)	0.64 (− 1.4 to 2.70)	0.537
CD4, every 100 cells/μl	− 0.03 (− 0.2 to 0.2)	0.713
Viral suppression	− 3.4 (− 5.7 to − 1.2)	0.003	− 3.2 (− 0.9 to − 5.4)	0.006
PHQ-9 ≥ 10 before DTG	− 2.8 (− 4.3 to − 1.3)	< 0.001	− 2.7 (− 1.2 to − 4.2)	< 0.001
PHQ-9 ≥ 15 before DTG	− 6.2 (− 8.6 to − 3.7)	< 0.001
EFV use before DTG	0.11 (− 1.1 to 1.3)	0.859

PHQ-9 change = PHQ-9 at 2nd assessment minus PHQ-9 at 1st assessment

Statistical method: Linear regression with PHQ-9 change as dependent variable

Factors with p < 0.1 in the univariable model were included into multivariable analysis

NS not significant, PHQ-9 Patient Health Questionnaire-9, EFV Efavirenz