Fig. 7.

BCYRN1/miR-490-3p/POU3F2 formed a network to accelerate HCC cells invasion and migration. a The elevating of invaded and migrated HepG2 cells caused by miR-490-3p inhibitor or pcDNA3.1-POU3F2 were limited by silencing of BCYRN1, **P < 0.01 vs. control, ^##P < 0.01 vs. miR-490-3p inhibitor, ^&&P < 0.01 vs. POU3F2-OE. b The descending of invaded and migrated BEL-7402 cells induced by miR-490-3p mimic or si-POU3F2 were restricted by overexpression of BCYRN1, **P < 0.01 vs. control, ^##P < 0.01 vs. miR-490-3p mimic, ^&&P < 0.01 vs. si-POU3F2