Table 2.

Distribution of microorganisms isolated from specimens taken from SBA and SAA groups

Organisms	No. of Isolates in SBA Group (N = 6516), n (%)	No. of Isolates in SAA Group (N = 2334), n (%)	P value
Bacteria	6256 (96.0%)	2138 (91.6%)	< 0.001
Gram-positive organism	1773 (27.2%)	577 (24.7%)	0.020
S. aureus	556 (8.5%)	232 (9.9%)	0.041
CNS	469 (7.2%)	105 (4.5%)	< 0.001
Streptococcus spp.	311 (4.8%)	64 (2.7%)	< 0.001
Enterococcus spp.	437 (6.7%)	176 (7.5%)	0.173
Gram-negative organism	4268 (65.5%)	1515 (64.9%)	0.607
Enterobacteriaceae	2777 (42.6%)	847 (36.3%)	< 0.001
E. coli	1008 (15.5%)	226 (9.7%)	< 0.001
K. pneumoniae	1037 (15.9%)	375 (16.1%)	0.863
Enterobacter spp.	237 (3.6%)	125 (5.4%)	< 0.001
Other Enterobacteriaceae bacteria	495 (7.6%)	121 (5.2%)	< 0.001
Non-fermenting bacteria	1296 (19.9%)	647 (27.7%)	< 0.001
Pseudomonas spp.	569 (8.7%)	236 (10.1%)	0.047
Acinetobacter spp.	487 (7.5%)	274 (11.7%)	< 0.001
Burkholderia spp.	32 (0.5%)	17 (0.7%)	0.185
S. maltophilia	114 (1.7%)	61 (2.6%)	0.01
Other non-fermenting bacteria	94 (1.4%)	59 (2.5%)	< 0.001
H. influenzae	150 (2.3%)	19 (0.8%)	< 0.001
M. catarrhalis	45 (0.7%)	2 (0.1%)	< 0.001
Other bacteria	215 (3.3%)	46 (2.0%)	0.001
Fungi	260 (4.0%)	196 (8.4%)	< 0.001
Candida spp.	233 (3.6%)	185 (7.9%)	< 0.001
Aspergillus spp.	20 (0.3%)	10 (0.4%)	0.386
Cryptococcus spp.	3 (0.0%)	0 (0.0%)	0.571*
Other fungi	4 (0.0%)	1 (0.0%)	0.854#

Abbreviations: SBA specimen taken before antibiotic therapy, SAA specimen taken after antibiotic therapy, S. aureus Staphylococcus aureus, CNS coagulase-negative Staphylococcus, E. coli Escherichia coli, K. pneumoniae Klebsiella pneumoniae, S. maltophilia Stenotrophomonas maltophilia, H. influenzae Haemophilus influenzae, M. catarrhalis Moraxella catarrhalis

*Fisher’s exact test

^# Corrected chi-square test