Table 1.
Patient characteristics
| Characteristic | Baseline | Oral Appliance | P Value |
|---|---|---|---|
| Sex, M:F | 52:41 |
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| Age, yr | 56.2 ± 11.0 |
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| BMI, kg/m2 | 30.5 ± 5.3 |
||
| Neck circumference, cm | 40.2 ± 4.1 |
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| Maximum possible advancement, mm | 10.4 ± 3.4 |
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| Final advancement, mm | 9.2 ± 3.0 |
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| Mandibular advancement, % maximum | 88.5 ± 14.8 |
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| AHI, total events/h | 30.6 [24.4–43.5] | 11.3 [5.5–19.1] | <0.001 |
| % reduction (ΔAHI) | 67.4 [42.5–83.1] |
||
| AHI, non-REM, events/h | 31.4 [21.5–48.6] | 7.3 [3.1–16.9] | <0.001 |
| AHI, REM, events/h | 48.8 [29.1–66.1] | 25.6 [6.1–45.3] | <0.001 |
| AHI, supine*, events/h | 52.9 [33.0–72.4] | 16.7 [8.7–38.4] | <0.001 |
| Arousal index, events/h | 43.5 [35.7–54.6] | 9.9 [4.4–16.5] | <0.001 |
| Minimum oxygen saturation, % | 80 [76–84] | 87 [81–90] | <0.001 |
| TST, min | 356 ± 65 | 363 ± 65 | 0.43 |
| REM sleep time, % TST | 16.8 ± 6.2 | 17.6 ± 6.9 | 0.45 |
| Supine sleep time*, % TST | 40.1 [26.3–69.3] | 37.0 [21.2–80.6] | 0.83 |
Definition of abbreviations: AHI = apnea–hypopnea index; BMI = body mass index; F = female; M = male; REM = rapid eye movement; TST = total sleep time.
On average, participants were typical patients with obstructive sleep apnea, middle aged, predominantly obese with moderate to severe obstructive sleep apnea. Continuous variables are presented as mean ± standard deviation or median [25th–75th centile].
*
Data available in n = 62.