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. 2020 Jan 6;15:1. doi: 10.1186/s13019-020-1051-3

Table 6.

Descriptive statistics of procedures and administered medications with results of regression analyses

Variablea Underwent Treatment/Procedure Patients Underwent the Treatment/Procedure pb
Yes No Overall Delayed Extubation Immediate/Early Extubation
N (%) N (%) N Median (Qrange) N Median (Qrange) N Median (Qrange)
Aortic cross clamp (min) 293 (83.7) 57 (16.3) 293 62.0 (52.5) 211 72.0 (60.9) 82 < 0.0001
Low Temperature (°C) 346 (98.9) 4 (1.1) 346 28.3 (13.3) 230 18.9 (12.0) 116 30.2 (4.9) < 0.0001
DHCA (min) 42 (12.0) 308 (88.0) 42 25.0 (33.0) 40 21.0 (33.5) 2 26.5 (1.00) 0.662
Urine (cc/kg) 330 (94.3) 20 (5.7) 330 5.7 (8.6) 214 5.1 (7.6) 116 7.43 (10.3) 0.002
Fentanyl (mcg/kg) 347 (99.1) 3 (0.9) 347 17.9 (21.7) 232 27.0 (17.4) 115 8.82 (10.7) < 0.0001
Morphine (mg/kg) 4 (1.1) 346 (98.9) 4 0.4 (2.0) 1 0.16 (0.00) 3 0.56 (3.60) NA
Propofol (mg/kg) 246 (70.3) 104 (29.7) 246 3.0 (3.6) 150 2.8 (4.27) 96 3.08 (3.0) 0.594
Dexmedetomidine (mcg/kg) 302 (86.3) 48 (13.7) 302 3.0 (2.5) 188 2.9 (2.70) 114 3.33 (2.2) 0.005
Roc uranium (mg/kg) 349 (99.7) 1 (0.3) 349 3.5 (2.6) 231 4.2 (2.7) 118 2.73 (1.0) 0.742
Neostigmine (mg/kg) 94 (26.9) 256 (73.1) 94 0.01 (0.01) 13 0.1 (0.04) 81 0.07 (0.0) 0.944
Sugammadex (mg/kg) 35 (10.0) 315 (90.0) 35 5.0 (4.1) 5 4.4 (1.00) 30 5.37 (4.1) NA
Midazolam (mg/kg) 21 (6.0) 329 (94.0) 21 0.3 (0.1) 12 0.3 (0.41) 9 0.33 (0.1) 0.676
Other Sedatives (mg/kg) 32 (9.1) 318 (90.9) 32 4.7 (3.2) 29 4.6 (2.4) 3 10.0 (18.0) NA
Mannitol (mg/kg) 218 (62.3) 132 (37.7) 218 407.2 (100.0) 148 409.0 (100.0) 70 406.0 (100.0) 0.661
Lasix (mg/kg) 298 (85.1) 52 (14.9) 298 0.5 (0.4) 195 0.6 (0.29) 103 0.3 (0.2) 0.008
NS Amount (cc/kg) 344 (98.3) 6 (1.7) 344 20.0 (14.6) 227 21.4 (15.9) 117 17.5 (11.5) 0.003
HFC (mg/kg) 300 (85.7) 50 (14.3) 300 98.7 (71.0) 208 137.0 (75.8) 92 70.1 (55.5) 0.129
Milrinone (mg/kg) 349 (99.7) 1 (0.3) 349 0.2 (0.1) 232 0.2 (0.06) 117 0.14 (0.03) 0.103
Epinephrine (mg/kg) 135 (38.6) 215 (61.4) 135 0.01 (0.01) 132 0.01 (0.01) 3 0.00 (0.02) 0.791
Vasopresin (mcg/kg) 6 (1.7) 344 (98.3) 6 0.0 (0.1) 6 0.1 (0.1) 0 0.00 NA
ICU EBL (cc/kg) 331 (94.6) 19 (5.4) 331 30.0 (35.0) 219 38.0 (47.0) 112 24.0 (16.5) 0.858
Intubation (days)# 245 (70.0) 105 (30.0) 346 2.0 (4.0) 229 3.0 (3.00) 117 0.0 (0.0) < 0.0001

Note. a 0 s in variables are excluded. # 0 s were NOT Excluded (Intubation Days)

b P-values are determined from median regression for Mannitol, Amount, and Epi; Poisson regression for Intubation days, and Log-Normal regression for other continuous variables. Extubation group (IE + EE vs. DE) was used as the main predictor adjusting for age, weight, and length as covariates.NAs are due to limited sample size. P < 0.05 are in bold character