Table 6.
Variablea | Underwent Treatment/Procedure | Patients Underwent the Treatment/Procedure | pb | ||||||
---|---|---|---|---|---|---|---|---|---|
Yes | No | Overall | Delayed Extubation | Immediate/Early Extubation | |||||
N (%) | N (%) | N | Median (Qrange) | N | Median (Qrange) | N | Median (Qrange) | ||
Aortic cross clamp (min) | 293 (83.7) | 57 (16.3) | 293 | 62.0 (52.5) | 211 | 72.0 (60.9) | 82 | < 0.0001 | |
Low Temperature (°C) | 346 (98.9) | 4 (1.1) | 346 | 28.3 (13.3) | 230 | 18.9 (12.0) | 116 | 30.2 (4.9) | < 0.0001 |
DHCA (min) | 42 (12.0) | 308 (88.0) | 42 | 25.0 (33.0) | 40 | 21.0 (33.5) | 2 | 26.5 (1.00) | 0.662 |
Urine (cc/kg) | 330 (94.3) | 20 (5.7) | 330 | 5.7 (8.6) | 214 | 5.1 (7.6) | 116 | 7.43 (10.3) | 0.002 |
Fentanyl (mcg/kg) | 347 (99.1) | 3 (0.9) | 347 | 17.9 (21.7) | 232 | 27.0 (17.4) | 115 | 8.82 (10.7) | < 0.0001 |
Morphine (mg/kg) | 4 (1.1) | 346 (98.9) | 4 | 0.4 (2.0) | 1 | 0.16 (0.00) | 3 | 0.56 (3.60) | NA |
Propofol (mg/kg) | 246 (70.3) | 104 (29.7) | 246 | 3.0 (3.6) | 150 | 2.8 (4.27) | 96 | 3.08 (3.0) | 0.594 |
Dexmedetomidine (mcg/kg) | 302 (86.3) | 48 (13.7) | 302 | 3.0 (2.5) | 188 | 2.9 (2.70) | 114 | 3.33 (2.2) | 0.005 |
Roc uranium (mg/kg) | 349 (99.7) | 1 (0.3) | 349 | 3.5 (2.6) | 231 | 4.2 (2.7) | 118 | 2.73 (1.0) | 0.742 |
Neostigmine (mg/kg) | 94 (26.9) | 256 (73.1) | 94 | 0.01 (0.01) | 13 | 0.1 (0.04) | 81 | 0.07 (0.0) | 0.944 |
Sugammadex (mg/kg) | 35 (10.0) | 315 (90.0) | 35 | 5.0 (4.1) | 5 | 4.4 (1.00) | 30 | 5.37 (4.1) | NA |
Midazolam (mg/kg) | 21 (6.0) | 329 (94.0) | 21 | 0.3 (0.1) | 12 | 0.3 (0.41) | 9 | 0.33 (0.1) | 0.676 |
Other Sedatives (mg/kg) | 32 (9.1) | 318 (90.9) | 32 | 4.7 (3.2) | 29 | 4.6 (2.4) | 3 | 10.0 (18.0) | NA |
Mannitol (mg/kg) | 218 (62.3) | 132 (37.7) | 218 | 407.2 (100.0) | 148 | 409.0 (100.0) | 70 | 406.0 (100.0) | 0.661 |
Lasix (mg/kg) | 298 (85.1) | 52 (14.9) | 298 | 0.5 (0.4) | 195 | 0.6 (0.29) | 103 | 0.3 (0.2) | 0.008 |
NS Amount (cc/kg) | 344 (98.3) | 6 (1.7) | 344 | 20.0 (14.6) | 227 | 21.4 (15.9) | 117 | 17.5 (11.5) | 0.003 |
HFC (mg/kg) | 300 (85.7) | 50 (14.3) | 300 | 98.7 (71.0) | 208 | 137.0 (75.8) | 92 | 70.1 (55.5) | 0.129 |
Milrinone (mg/kg) | 349 (99.7) | 1 (0.3) | 349 | 0.2 (0.1) | 232 | 0.2 (0.06) | 117 | 0.14 (0.03) | 0.103 |
Epinephrine (mg/kg) | 135 (38.6) | 215 (61.4) | 135 | 0.01 (0.01) | 132 | 0.01 (0.01) | 3 | 0.00 (0.02) | 0.791 |
Vasopresin (mcg/kg) | 6 (1.7) | 344 (98.3) | 6 | 0.0 (0.1) | 6 | 0.1 (0.1) | 0 | 0.00 | NA |
ICU EBL (cc/kg) | 331 (94.6) | 19 (5.4) | 331 | 30.0 (35.0) | 219 | 38.0 (47.0) | 112 | 24.0 (16.5) | 0.858 |
Intubation (days)# | 245 (70.0) | 105 (30.0) | 346 | 2.0 (4.0) | 229 | 3.0 (3.00) | 117 | 0.0 (0.0) | < 0.0001 |
Note. a 0 s in variables are excluded. # 0 s were NOT Excluded (Intubation Days)
b P-values are determined from median regression for Mannitol, Amount, and Epi; Poisson regression for Intubation days, and Log-Normal regression for other continuous variables. Extubation group (IE + EE vs. DE) was used as the main predictor adjusting for age, weight, and length as covariates.NAs are due to limited sample size. P < 0.05 are in bold character