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. Author manuscript; available in PMC: 2020 Dec 1.
Published in final edited form as: Biomaterials. 2019 Sep 5;223:119476. doi: 10.1016/j.biomaterials.2019.119476

Figure 5. NM23TC pharmacokinetics:

Figure 5.

Sprague-Dawley rats were given a single IM injection of 75 mg/kg 3TC equivalents as NM23TC. (A) Prodrug concentrations in whole blood were measured at days 1,7,14, 21, and 28. (B) Prodrug levels in liver were measured at days 1 and 28. Prodrug (red) and 3TC-TP (magenta) levels in (C) lymph node, and (D) spleen were determined at days 1 and 28.