Figure 1.

Time to first HYPO-broad: symptomatic hypoglycaemia adverse event with plasma glucose ≤70 mg/dL, or hypoglycaemia adverse event with plasma glucose <54 mg/dL, or severe hypoglycaemia adverse event. Hazard ratio from Cox regression model. Based on Kaplan–Meier estimates; hazard ratio based on a Cox proportional-hazards model, with study group, age, sex, baseline body mass index, baseline glycated haemoglobin level, baseline estimated glomerular filtration rate, and geographic region as factors. HR, hazard ratio.