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The key observations of this article. Upper panel: relationship between occurrence vs. non-occurrence of hypoglycaemia and select outcomes in the placebo group of EMPA-REG OUTCOME. Lower panel: Effect of empagliflozin on select outcomes in the total population and by occurrence of hypoglycaemia in EMPA-REG OUTCOME. Hypoglycaemia defined as symptomatic hypoglycaemia with plasma glucose ≤70 mg/dL, any hypoglycaemia with PG <54 mg/dL, or severe hypoglycaemia.
