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. 2020 Jan 6;20:5. doi: 10.1186/s12935-019-1071-z

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© The Author(s) 2020

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 1 — Circ_LARP4 expression is markedly down-regulated in OC cell lines. a Utilizing quantitative real-time polymerase chain reaction (qRT-PCR) to assess the expression of OC cell lines (SKOV3, A2780, SW626, OVCAR3, OVCAR4) and normal ovarian epithelial cells (HOSEpiC). b RNA expression of circ_LARP4 and LARP4 in two cells (SKOV3 and A2780) treated with actinomycin D was tested by qRT-PCR analysis. c The qRT-PCR analysis was used to the expression of circ_LARP4 and linear LARP4 with adding RNase R. d Circ_LARP4 expressions in cDNA and gDNA was measured by qRT-PCR analysis. All results were displayed as the mean ± SD. *P < 0.05, **P < 0.01