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. 2020 Jan 6;17:2. doi: 10.1186/s11556-019-0234-1

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© The Author(s) 2020

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 2 — Study design and visual presentation of CAT, IAT and CG program. a = watts equivalent to 70% of HR_max or 50% of MTP. Base = watts equivalent to 60% of HR_max. Peak = watts equivalent to 80% of HR_max or MTP – 10 watts. Abbreviations: IMET, Incremental Maximal Exercise Test; BDNF, Brain Derived Neurotrophic Factor; QoL-AD, Quality of life of Alzheimer disease; 6MWT, 6 Minutes walking – test