Table 2.
Baseline characteristics of subgroups of non-PCOS and PCOS without HA participants
| Control | PCOS-N | |||
|---|---|---|---|---|
| BMI < 24 | BMI ≥ 24 | BMI < 24 | BMI ≥ 24 | |
| n | 11 | 12 | 11 | 16 |
| Age (years) | 27.00 (26.00–29.00) | 26.50 (22.5–28.75) | 26.00 (24.00–29.00) | 27.00 (25.50–29.75) |
| BMI (kg/m2) | 21.23 (19.35–22.20) | 27.39 (25.99–28.90)a | 20.83 (19.20–22.58)b | 27.19 (24.65–29.59) ac |
| LH (IU/L) | 5.21 (4.21–5.63) | 6.16 (5.00–11.13) | 8.72 (6.67–15.23) | 11.33 (7.26–20.24)a |
| FSH (IU/L) | 6.96 (5.32–9.36) | 6.28 (5.97–7.41) | 5.43 (3.20–8.51) | 5.82 (3.60–7.17) |
| LH/FSH | 0.79 (0.60–0.91) | 1.01 (0.82–1.54) | 1.62 (1.33–2.42)a | 1.90 (1.36–2.87)ab |
| P (nmol/L) | 0.70 (0.60–0.91) | 0.52 (0.37–0.98) | 0.77 (0.45–1.75) | 0.51 (0.38–0.88) |
| E2 (pmol/L) | 130.80 (94.00–175.40) | 168.65 (132.85–381.08) | 230.00 (120.40–585.30) | 159.70 (108.4–235.35) |
| T (nmol/L) | 1.10 (0.61–1.37) | 0.90 (0.76–1.59) | 1.37 (1.09–1.56) | 1.18 (0.95–1.40) |
| FT (pmol/L) | 7.42 (5.95–9.93) | 6.92 (6.51–10.11) | 6.01 (4.93–10.45) | 9.99 (6.71–13.34) |
| FBG (mmol/L) | 5.60 (5.20–6.00) | 5.70 (5.05–5.98) | 5.80 (5.60–6.30)b | 6.10 (5.70–6.58) |
| FINS (μIU/ml) | 8.99 (7.40–10.80) | 16.88 (12.53–20.51)a | 12.78 (8.98–14.65) | 15.79 (11.95–30.87)a |
| HOMA-IR | 2.38 (1.91–2.59) | 3.98 (3.00–5.22)a | 3.57 (2.27–3.65) | 4.16 (3.15–8.99)a |
| Cr (μmol/L) | 64.40 (59.00–66.20) | 64.30 (61.08–66.50) | 59.70 (56.20–69.00) | 64.95 (63.50–67.28) |
| CRP (mg/L) | 1.02 (0.46–2.61) | 1.56 (1.06–3.16) | 0.84 (0.20–1.37) | 2.15 (1.53–5.58)ac |
| CHOL (mmol/L) | 4.80 (4.01–5.34) | 4.75 (4.31–5.11) | 4.41 (3.96–4.81) | 5.11 (4.69–6.01) |
| TG (mmol/L) | 1.03 (0.90–1.24) | 1.01 (0.80–1.86) | 0.81 (0.60–1.43) | 1.53 (1.13–2.24) |
| ALT (U/L) | 13.00 (8.00–19.00) | 24.00 (18.25–35.00) | 15.00 (10.00–21.00) | 28.00 (15.75–36.25)ac |
| AST (U/L) | 16.00 (13.00–17.00) | 20.00 (16.25–28.00)a | 17.00 (15.00–22.00) | 20.00 (16.50–21.75) |
| HDL (mmol/L) | 1.42 (1.27–1.59) | 1.40 (1.23–1.59) | 1.63 (1.31–1.85) | 1.25 (1.13–1.51) |
| LDL (mmol/L) | 2.72 (2.28–3.49) | 2.77 (2.26–3.38) | 2.44 (1.90–3.01) | 2.85 (2.52–3.39) |
| sdLDL (mmol/L) | 0.87 (0.73–1.06) | 0.84 (0.60–1.17) | 0.77 (0.57–0.95) | 1.18 (0.76–1.54) |
| APOA (g/L) | 1.40 (1.21–1.64) | 1.35 (1.26–1.63) | 1.46 (1.33–1.57) | 1.38 (1.30–1.53) |
| APOB (g/L) | 0.73 (0.64–0.80) | 0.72 (0.62–0.83) | 0.65 (0.54–0.71) | 0.78 (0.64–0.87) |
Data are presented as median (interquartile range). aP < 0.05 versus control-normal weight participants, bP < 0.05 versus control-obese weight participants, cP < 0.05 versus PCOS-normal weight participants. BMI Body mass index, LH Luteinizing hormone, FSH Follicle-stimulating hormone, P Progesterone, E2 Estradiol, T Testosterone, FT Free testosterone, FBG Fasting blood glucose, FINS Fasting plasma insulin, HOMA-IR Homeostasis model assessment insulin resistance index, Cr Creatinine, CRP C-reactive protein, CHOL Cholesterol, TG Triglyceride, ALT Alanine transaminase, AST Aspartate aminotransferase, LDL Low-density lipoprotein, HDL High-density lipoprotein, sdLDL Small dense LDL, APOA Apolipoprotein A, APOB apolipoprotein B