Table 2.
Adverse Drug Events of Patients With Myositis-Related Interstitial Lung Disease Treated With Azathioprine and Mycophenolate Mofetil
| Adverse Event | Azathioprine (n = 66) |
Mycophenolate Mofetil (n = 44) |
All |
|---|---|---|---|
| No. (%) | No. (%) | No. (%) | |
| Transaminitis | 10 (15.2)a | 1 (2.3) | 11 (10)b |
| Nausea | 3 (4.5)a | 1 (2.3) | 4 (3.6) |
| Leukopenia | 3 (4.5) | 1 (2.3) | 4 (3.6) |
| Pancytopenia | 1 (1.5) | 0 | 1 (0.9) |
| Pneumonia | 1 (1.5) | 0 | 1 (0.9) |
| Rash | 1 (1.5) | 0 | 1 (0.9) |
| Insomnia | 0 | 1 (2.3) | 1 (0.9) |
| Abdominal pain | 0 | 1 (2.3) | 1 (0.9) |
| Diarrhea | 2 (3) | 0 | 2 (1.8) |
| Other | 1 (1.5) | 1 (2.3) | 2 (1.8) |
| Total | 22 (33.3) | 6 (13.6) | 28 (25.5)b |
a
These patients experienced both nausea and transaminitis.
b
P = .04.