Table 1.
Stage | No. at risk | 5-year PFS (95% CI) | p-value | No. at risk | 5-year DSS (95% CI) | p-value | |
---|---|---|---|---|---|---|---|
AS | I(A*) | 100 | 86.5(76.2,92.5) | < 0.001** | 100 | 92.9(83.4,97.0) | 0.001** |
II | 371 | 82.0(77.0,86.0) | 0.001# | 371 | 90.6(86.3,93.6) | 0.080# | |
IIA | 240 | 87.9(82.4,91.9) | 240 | 92.7(87.7,95.7) | |||
IIB | 131 | 71.0(60.9,79.0) | 131 | 86.2(76.8,92.0) | |||
III | 140 | 50.9(41.1,59.8) | 0.045△ | 140 | 74.1(64.2,81.7) | 0.099△ | |
IIIA | 78 | 56.6(43.7,67.6) | 78 | 80.4(67.8,88.5) | |||
IIIB | 29 | 55.2(28.6,75.4) | 29 | 51.4(23.1,73.9) | |||
IIIC | 33 | 34.9(18.3,52.2) | 33 | 70.4(46.9,85.0) | |||
PS | I | 100 | 86.5(76.2,92.5) | < 0.001** | 100 | 92.9(83.4,97.0) | < 0.001** |
IA | 3 | NA | NA | 3 | NA | NA | |
IB | 97 | 86.0(75.4,92.3) | 97 | 92.7(88.5,97.0) | |||
II | 291 | 83.9(78.3,88.2) | 0.002# | 291 | 91.9(87.2,94.9) | 0.209# | |
IIA | 240 | 87.9(82.4,91.9) | 240 | 92.7(89.7,95.7) | |||
IIB | 51 | 64.1(46.1,77.5) | 51 | 87.3(79.4,95.1) | |||
III | 220 | 60.1(52.3,66.9) | < 0.001△ | 220 | 78.2(70.7,83.9) | 0.023△ | |
IIIA | 83 | 74.7(62.2,83.6) | 83 | 85.5(78.7,92.3) | |||
IIIB | 26 | 73.7(50.4,87.3) | 26 | 83.5(72.5,94.5) | |||
IIIC | 111 | 44.9(34.0,55.1) | 111 | 70.7(61.8,79.7) |
**Log-rank test comparing proportions among all stage; #Log-rank test comparing proportions among Stage II; △Log-rank test comparing proportions among Stage III; *No case was classified as anatomic stage IB in this cohort
TNBC triple negative breast cancer, AS anatomic stage, PS prognosis stage, PFS progression-free survival, DSS disease specific survival, CI confidence interval