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. 2020 Jan 6;20:18. doi: 10.1186/s12885-019-6494-3

Table 1.

5-year Progression-Free Survival and Disease-Specific Survival by Anatomic and Prognosis Stage of TNBCs included in SYSUCC-PWH cohort (N = 611)

Stage No. at risk 5-year PFS (95% CI) p-value No. at risk 5-year DSS (95% CI) p-value
AS I(A*) 100 86.5(76.2,92.5) < 0.001** 100 92.9(83.4,97.0) 0.001**
II 371 82.0(77.0,86.0) 0.001# 371 90.6(86.3,93.6) 0.080#
 IIA 240 87.9(82.4,91.9) 240 92.7(87.7,95.7)
 IIB 131 71.0(60.9,79.0) 131 86.2(76.8,92.0)
III 140 50.9(41.1,59.8) 0.045 140 74.1(64.2,81.7) 0.099
 IIIA 78 56.6(43.7,67.6) 78 80.4(67.8,88.5)
 IIIB 29 55.2(28.6,75.4) 29 51.4(23.1,73.9)
 IIIC 33 34.9(18.3,52.2) 33 70.4(46.9,85.0)
PS I 100 86.5(76.2,92.5) < 0.001** 100 92.9(83.4,97.0) < 0.001**
 IA 3 NA NA 3 NA NA
 IB 97 86.0(75.4,92.3) 97 92.7(88.5,97.0)
II 291 83.9(78.3,88.2) 0.002# 291 91.9(87.2,94.9) 0.209#
 IIA 240 87.9(82.4,91.9) 240 92.7(89.7,95.7)
 IIB 51 64.1(46.1,77.5) 51 87.3(79.4,95.1)
III 220 60.1(52.3,66.9) < 0.001 220 78.2(70.7,83.9) 0.023
 IIIA 83 74.7(62.2,83.6) 83 85.5(78.7,92.3)
 IIIB 26 73.7(50.4,87.3) 26 83.5(72.5,94.5)
 IIIC 111 44.9(34.0,55.1) 111 70.7(61.8,79.7)

**Log-rank test comparing proportions among all stage; #Log-rank test comparing proportions among Stage II; Log-rank test comparing proportions among Stage III; *No case was classified as anatomic stage IB in this cohort

TNBC triple negative breast cancer, AS anatomic stage, PS prognosis stage, PFS progression-free survival, DSS disease specific survival, CI confidence interval