Table 1.
Three Types of Central Nervous System Bacillus cereus Infection
| Post-Surgical Procedure/Device Infection | Neonatal Infection | Severe Neutropenia | |
|---|---|---|---|
| Risk Population | Ommaya reservoir | Premature birth: 32 (27–36) weeks | WBC count <100/uL |
| Post intrathecal injection | Low body weight infant:1500 (830–3760) g | Induction therapy against AML | |
| Disease Onset | Several days after procedures | 7 (1–49) days after birth | Around 10 days of neutropenia |
| Mode of Infection | Meningitis | Meningoencephalitis | Necrotizing meningoencephalitis |
| Ventriculitis | Cerebral hemorrhage | ||
| Brain abscess | Subarachnoid hemorrhage | ||
| Clinical Course and Prognosis | Responds well to antimicrobial therapy | Progresses within hours | Progresses within hours |
| Leads to death within days | Leads to death within days | ||
| Cerebrospinal Fluid Findings | Up to 105 cells /mm3 | Around 102–3 cells /mm3 | Around 102 cells /mm3 |
| Mortality rate | Low | 75% (12/14 cases) | 79% (11/14 cases) |
| References | 3 | 3, 4 | 3, 6–14 |