Figure 1.
Treatment course schema. GM-CSF (250 mg/m2 subcutaneously) was given on days 1 through 2 and days 8 through 14. Hu14.18-IL2 (12 mg/m2/dose) was given as a four-hour intravenous infusion on days 4 through 6. Isotretinoin (160 mg/m2/day, divided twice daily) was given for 14 days starting on day 11.
*Hold GM-CSF 24 hours prior and 24 hours after hu14.18-IL2
**Stop on day 24