Table 5:
Development of anti-hu14.18-IL2 antibody in relation to response
| Test | Factor | N | Number of responders | p-value |
|---|---|---|---|---|
| Anti-IC | Negative Positive or intermediate |
14 12 |
2 (14.3%) 3 (25.0%) |
0.6348 |
| Anti-IC | Negative Positive |
14 5 |
2 (14.3%) 1 (20.0%) |
1.0000 |
| Anti-IC | Negative or Intermediate Positive |
21 5 |
4 (19.0%) 1 (20.0%) |
1.0000 |
The peak anti-IC level for each of 26 patients evaluable for response with serum available by bridging-ELISA method was characterized as: negative (<0.5 OD); intermediate (0.5 −2.0 OD); or positive (>2.0 OD).