Fig. 2.

Kinetic changes in absolute monocyte count and lymphocyte count. a The monocyte count in patients with dengue hemorrhagic fever (DHF) surged on day 5. b In comparison to patients with primary dengue, absolute monocyte count in patients with secondary infection increased on day 5, and became statistically significant on days 6-7. Absolute monocyte count was increased to a greater extent by dengue virus type-2 (DENV2) infection than by DENV3 infection (c), while lymphocyte count was increased to a greater extent by DENV3 than DENV2 infection after day 6 (f). Absolute lymphocyte count increased progressively in all patient groups (d) and showed no difference between primary and secondary dengue infections (e). Two-way ANOVA with the Scheffe test was used for statistical analysis. The normal range of the cell counts is outlined between the dashed lines. Asterisks designate statistical significance levels: * p < 0.05, ** p < 0.01, and *** p < 0.001.