TABLE 3.

Virologic and immunologic correlates of time to viral rebound in each age group

Variable	Infants			Adults
	Kendall's tau	P value		Kendall's tau	P value
		Unadjusted	Adjusted		Unadjusted	Adjusted
Preselected variables
Plasma VL at ART starta	−0.786	0.032	NAe	−0.886	0.022	NA
ADCC antibody titer on ARTa	−0.414	0.251	NA	−0.701	0.064	NA
CD4+ CD69+ T cells on ARTb	0.276	0.444	NA	−0.078	0.837	NA
CH505 T/F-neutralizing antibody titer at ART starta	−0.54	0.152	NA	−0.322	0.404	NA
Exploratory variables
Virologic and humoral responses
Peak plasma VLa	0	1	1	−0.856	0.024	0.04
CH505 gp120-specific IgG pre-ARTa	−0.69	0.056	0.14	−0.856	0.024	0.04
CH505 gp120-specific IgG on ARTa	−0.69	0.056	0.14	−0.701	0.064	0.08
Tier 1 MW965-neutralizing antibody pre-ARTa	−0.552	0.126	0.158	−0.856	0.024	0.04
sCD4-blocking antibodies pre-ARTc	−0.552	0.126	0.158	−0.545	0.15	0.15
CD4+ T cell phenotypes and inflammatory responses
CD4+ T cells pre-ARTb	0.138	0.702	0.936	0.078	0.837	0.837
CD4+ T cells on ARTb	0	1	1	0.234	0.537	0.781
HLA-DR+ CD4+ T cells on ARTb	0.276	0.444	0.936	−0.078	0.837	0.837
Ki67+ CD4+ T cells on ARTb	−0.276	0.444	0.936	0.078	0.837	0.837
PD-1+ CD4+ T cells on ARTb	0.138	0.702	0.936	0.545	0.15	0.781
G-CSF on ARTb	0.357	0.33	0.936	−0.418	0.289	0.781
IL-12 on ARTd	−0.357	0.33	0.936	−0.261	0.511	0.781
IL-15 on ARTd	−0.138	0.702	0.936	0.322	0.404	0.781
IL-18 on ARTd	0.552	0.126	0.936	0.405	0.343	0.781
IL-1RA on ARTd	0.138	0.702	0.936	0.389	0.304	0.781
IL-8 on ARTd	0.138	0.702	0.936	0.078	0.837	0.837
MCP-1 on ARTd	−0.414	0.251	0.936	−0.234	0.537	0.781
MIP-1α on ARTd	0.077	0.838	0.967	0.405	0.343	0.781
TNF-α on ARTd	0.357	0.33	0.936	0.234	0.537	0.781
VEGF on ARTd	−0.071	0.846	0.967	0.087	0.827	0.837
sCD40L on ARTd	0	1	1	−0.234	0.537	0.781

^aValues are expressed as log₁₀.

^bValues are expressed as absolute counts per nanoliter of blood.

^cValues are expressed as percentages.

^dValues are expressed as concentrations in pg/mL.

^eNA, not applicable since multiple adjustment was not performed on preselected parameters.