. 2019 Oct 16;9(4):124–130. doi: 10.1556/1886.2019.00021

Table 4.

Explorative linear regression model with backward selection for the global model with patients with S. aureus and/or E. coli infections. Association with the outcome parameter duration of hospital stay

Association with the outcome parameter duration of hospital stay	Global modeling with both patients with S. aureus and patients with E. coli		Modeling with patients with S. aureus		Modeling with patients with E. coli
	Odds ratio with 0.95 CI	P value	Odds ratio with 0.95 CI	P value	Odds ratio with 0.95 CI	P value
Biopsies and invasive foreign material	–1.36 (–2.23, –0.49)	0.002	n.a.	n.a.	–2.00 (–3.14, –0.88)	0.001
Blood cultures	n.a.	n.a.	1.40 (0.08, 2.71)	0.037	–3.15 (–4.49, –1.81)	<0.001
Bronchial lavage	n.a.	n.a.	n.a.	n.a.	–5.51 (–8.45, –2.56)	<0.001
Respiratory secretions	n.a.	n.a.	2.16 (0.52, 3.80)	0.010	–2.89 (–5.48, –0.29)	0.029
Aspirates	n.a.	n.a.	n.a.	n.a.	–2.55 (–4.66, –0.44)	0.018
Wound swabs	–1.16 (–1.98, –0.34)	0.005	n.a.	n.a.	n.a.	n.a.
Gastroenterology	3.18 (2.11, 4.25)	<0.001	5.18 (2.84, 7.52)	<0.001	2.57 (1.36, 3.79)	<0.001
Cardiovascular disease	1.68 (0.50, 2.85)	0.005	n.a.	n.a.	2.26 (0.70, 3.81)	0.005
Rheumatology and neoplasia	2.90 (1.79, 4.01)	<0.001	2.98 (1.01, 4.06)	0.003	2.86 (1.54, 4.17)	<0.001
Pulmonary disease	2.01 (0.72, 3.30)	0.002	n.a.	n.a.	2.83 (1.27, 4.38)	<0.001
Other diseases	2.79 (1.14, 4.43)	0.001	3.15 (0.19, 6.19)	0.037	2.39 (0.45, 4.32)	0.016
Urologic disease	1.99 (0.85, 3.13)	0.001	n.a.	n.a.	2.18 (0.99, 3.38)	<0.001
Previous antibiotic therapy	1.46 (0.79, 2.13)	<0.001	2.10 (1.01, 3.20)	<0.001	n.a.	n.a.
CRP	–0.47 (–0.80, –0.14)	0.005	–0.73 (–1.28, –0.18)	0.010	–0.44 (–0.83, –0.04)	0.032
Age	–0.036 (–0.05, –0.02)	<0.001	–0.04 (–0.06, –0.01)	0.002	n.a.	n.a.
Third-generation cephalosporin resistance	n.a.	n.a.	n.a.	n.a.	2.59 (1.38, 3.81)	<0.001
Tetracycline resistance	n.a.	n.a.	2.22 (0.25, 4.18)	0.027	n.a.	n.a.
Fusidic acid resistance	n.a.	n.a.	5.67 (2.26, 9.08)	0.001	n.a.	n.a.
Ciprofloxacin resistance	n.a.	n.a.	n.a.	n.a.	0.81 (–0.15, 1.76)	0.097
Superficial infection	n.a.	n.a.	n.a.	n.a.	–2.46 (–3.71, –1.21)	<0.001
Superficial infection	N 1883, adjusted R² 0.3987		N 918, adjusted R² 0.3863		N 774, adjusted R² 0.5340

Coefficients >0 indicate a prolonging association with the endpoint days to discharge (parameter extends on average by the shown number of days), coefficients <0 indicate a shortening association (parameter reduces on average by the shown number of days).