Table 2.
Screening performance characteristics of S100B and neuron specific enolase (NSE) biomarkers in differentiating acute vertigo cases with central cause
| Characteristics | S100B | NSE |
|---|---|---|
| True positive | 54 | 66 |
| True negative | 23 | 17 |
| False positive | 2 | 2 |
| False negative | 6 | 0 |
| Sensitivity | 90.00 (78.83 - 95.86) | 100.00 (93.14 – 100.00) |
| Specificity | 92.00 (72.49 - 98.60) | 89.47 (65.46 - 98.15) |
| Positive predictive value | 96.42 (86.61 – 99.37) | 97.05 (88.83 – 99.48) |
| Negative predictive value | 79.31 (59.73 – 91.29) | 100.00 (77.07 – 100.00) |
| Positive likelihood ratio | 27.00 (6.91 -105.39) | 33.00 (8.41 – 129.34) |
| Negative likelihood ratio | 0.26 (0.12 – 0.54) | 0.00 (0.00 – NaN) |
| Total accuracy | 90.3 (80.7- 99.8) | 96.9 (93.7 - 100.0) |
Data are presented with 95% confidence interval (CI). NaN: the calculation cannot be performed because the values entered include one or more instances of zero.