Table 3.
Factors that influenced the overall survival (OS) of patients with esophageal cancer assessed by Cox regression analysis.
| Characteristics | Univariate analysis | Multivariate analysis | ||
|---|---|---|---|---|
| HR (95% CI) | P-value | HR (95% CI) | P-value | |
| Gender: (Male: Female) | 2.618 (1.285–5.337) | 0.008* | 1.827 (0.765–4.364) | 0.175 |
| Age (years): (<60: ≥60) | 1.093 (0.630–1.894) | 0.752 | 1.543 (0.828–2.878) | 0.172 |
| Tumor size: (≥4.5 cm: <4.5 cm) | 1.674 (1.014–2.763) | 0.044* | 1.363 (0.792–2.346) | 0.264 |
| Stage: (III–IV: I–II) | 0.805 (0.436–1.485) | 0.487 | 0.723 (0.377–1.385) | 0.328 |
| Tumor invasion: (T3/T4: T1/T2) | 2.950 (0.923–7.127) | 0.008* | 1.613 (0.898–5.021) | 0.087 |
| Lymph node metastasis: (present: absent) | 2.518 (1.290–3.609) | 0.003* | 1.689 (0.928–3.074) | 0.086 |
| Nectin-4 expression: (high: low) | 1.704 (1.027–2.825) | 0.039* | 1.795 (1.042–3.092) | 0.035* |
HR – hazard ratio; CI – confidence interval. Univariate and multivariate Cox regression analysis. The clinical data is incomplete sample have been removed.
*
P<0.05 was considered as statistically significant.