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. Author manuscript; available in PMC: 2020 Jan 7.
Published in final edited form as: Ann Intern Med. 2014 Mar 18;160(6):380–388. doi: 10.7326/M13-1419

Table.

Characteristics of Patients With a Principal Diagnosis of Pneumonia or Sepsis/Respiratory Failure

Characteristic Principal Diagnosis, n (%) P Value*
Pneumonia Sepsis/Respiratory Failure
Median age, y 72 (57–82) 71 (59–81) 0.005
Sex <0.001
 Male 81 639 (46.0) 35 136 (48.5)
 Female 95 875 (54.0) 37 366 (51.5)
Comorbid conditions
 Congestive heart failure 33 115 (18.7) 16 191 (22.3) <0.001
 Valvular disease 11 295 (6.4) 4451 (6.1) 0.35
 Pulmonary circulation disease 7874 (4.4) 4419 (6.1) <0.001
 Peripheral vascular disease 9829 (5.5) 4295 (5.9) 0.060
 Hypertension 88 085 (49.6) 28 081 (38.7) <0.001
 Paralysis 4110 (2.3) 2474 (3.4) <0.001
 Other neurologic disorders 17 812 (10.0) 7741 (10.7) 0.002
 Chronic pulmonary disease 85 491 (48.2) 35 974 (49.6) 0.020
 Diabetes 43 101 (24.3) 16 391 (22.6) <0.001
 Hypothyroidism 21 726 (12.2) 7005 (9.7) <0.001
 Liver disease 3215 (1.8) 1679 (2.3) <0.001
 Ulcer 38 (0.02) 14 (0.02) 0.98
 AIDS 17 (0.01) 51 (0.07) <0.001
 Lymphoma 2304 (1.3) 843 (1.2) 0.070
 Metastatic cancer 4489 (2.5) 2160 (3.0) <0.001
 Solid tumor without metastasis 5091 (2.9) 1895 (2.6) <0.001
 Rheumatoid arthritis/collagen vascular disease 6063 (3.4) 1930 (2.7) <0.001
 Obesity 14 488 (8.2) 5827 (8.0) 0.030
 Weight loss 8781 (5.0) 7058 (9.7) <0.001
 Chronic blood loss anemia 1011 (0.6) 631 (0.9) <0.001
 Deficiency anemias 38 830 (21.7) 16 721 (23.1) 0.020
 Alcohol abuse 4231 (2.4) 2006 (2.8) 0.001
 Drug abuse 3389 (1.9) 1358 (1.9) 0.120
 Psychoses 7212 (4.1) 2822 (3.9) 0.004
 Depression 19 842 (11.2) 6289 (8.7) <0.001
 Renal failure 21 552 (12.1) 10 443 (14.4) <0.001
Hospital characteristics
 Bed size <0.001
  ≤200 beds 37 290 (21.0) 11 919 (16.4)
  201–400 beds 68 349 (38.5) 29 298 (40.4)
  ≥401 beds 71 875 (40.5) 31 285 (43.2)
 Rural/urban status <0.001
  Rural 24 936 (14.1) 7914 (10.9)
  Urban 152 578 (86.0) 64 588 (89.1)
 Teaching status 0.090
  Teaching 60 342 (34.0) 26 393 (36.4)
  Nonteaching 117 172 (66.0) 46 109 (63.6)
 Region 0.140
  Northeast 30 949 (17.4) 9900 (13.7)
  Midwest 37 967 (21.4) 17 281 (23.8)
  West 29 299 (16.5) 13 036 (18.0)
  South 79 299 (44.7) 32 285 (44.5)
In-hospital mortality 6297 (3.6) 11 742 (16.2) <0.001
Total 177 514 (71.0) 72 502 (29.0)
*

Accounting for clustering of patients within hospitals.

Values in parentheses are 25th, 75th percentiles.