Table 1. Analytical sensitivity for the detecting genetic resistance markers of Inh (H) and Rif (R) reported as LoD95HR of BD-MAX and XP-Ultra determined by mathematical interpolation.
| BD-MAX cfu/ml (CI95%) | XP-Ultra cfu/ml (CI95%) | |||||||
|---|---|---|---|---|---|---|---|---|
| Matrix | MTB | Rif | Inh | MTB | Rif | |||
| H37Rv (WT) | H37Rv (WT) | T837 (MDR) | H37Rv (WT) | T837 (MDR) | H37Rv (WT) | H37Rv (WT) | T837 (MDR) | |
| Sputum | 2.1 (0.9–23.3) | 7.8 (2.7–462.8) | 17.6 (9.0–477.6) | 19.4 (5.8–993.4) | 17.6 (9.0–477.6) | 3.1 (1.2–88.9) | 49.3 (11–9,544) | 63.2 (33.5–271.4) |
| MUCAS | 6.3 (2.9–31.8) | 44.1 (12.3–2,104) | 1,388.2 (53.3-NA) | 2,652.8 (1381–10,171) | 212.8 (30.0-NA) | 1.5 (0.7–5.0) | 72.6 (26–609) | 194.8 (54.9–27,421) |
| Saline | 2.3 (1.1–12.0) | 5.3 (2.1–124.6) | 7.7 (4.6–16.5) | 4.1 (1.6–228.3) | 7.7 (4.6–16.5) | 11.5 (5.6–47.3) | 56.5 (24.3–272) | 2,165.9 (591–35,996) |