Table 2. Top 20 inguinal hernia-causative proteins based on the number of overlapping clusters.
Rank | Uniprot | Protein | Cluster # | Rank | Uniprot | Protein | Cluster # |
---|---|---|---|---|---|---|---|
1 | P27986 | PIK3R1 | 207** | 11 | P11362 | FGFR1 | 23 |
2 | Q06124 | PTPN11 | 127* | 12 | P0CG48 | UBC | 19 |
3 | Q07889 | SOS1 | 101 | 13 | O75369 | FLNB | 16 |
4 | P36897 | TGFBR1 | 68 | 14 | Q13285 | NR5A1 | 14 |
5 | P37173 | TGFBR2 | 56 | 15 | P43694 | GATA4 | 11 |
6 | P60953 | CDC42 | 50 | 16 | P61812 | TGFB2 | 11 |
7 | P01116 | KRAS | 40 | 17 | P62993 | GRB2 | 11 |
8 | P11112 | HRAS | 37 | 18 | P36894 | BMPR1A | 9 |
9 | P07949 | RET | 26 | 19 | P10600 | TGFB3 | 8 |
10 | P16234 | PDGFRA | 23 | 20 | P35916 | FLT4 | 8 |
* > mean ± (τ·SD)/2
** > mean ± τ·SD