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. 2019 Nov 1;98(44):e17552. doi: 10.1097/MD.0000000000017552

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Copyright © 2019 the Author(s). Published by Wolters Kluwer Health, Inc.

This is an open access article distributed under the terms of the Creative Commons Attribution-Non Commercial License 4.0 (CCBY-NC), where it is permissible to download, share, remix, transform, and buildup the work provided it is properly cited. The work cannot be used commercially without permission from the journal. http://creativecommons.org/licenses/by-nc/4.0

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Reduced anxiety by CEC in patients with HCC who underwent surgery. HADS-A score in CEC group was lower compared to control group at M9 and M12 (A) and HADS-A score reduction (M12-M0) was greater in CEC group compared with control group (B). At M12, the percentage of anxiety patients was lower in CEC group compared with control group (C), whereas the anxiety severity was similar between the 2 groups (D). The comparisons between 2 groups were conducted using independent-sample t test, Chi-square test and Wilcoxon rank sum test. P < .05 was considered significant. ^∗P < .05. CEC = comprehensive education and care, HADS-A = Hospital Anxiety and Depression Scale-Anxiety, HCC = hepatocellular carcinoma, NS = nonsignificant.