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The applications of the GO hydrogel scaffolds in a liver-on-a-chip system. (a) Schematic of the construction of the liver-on-a-chip. (b) Image of the GO hydrogel scaffold-integrated liver-on-a-chip. (c–e) Albumin secretion (c), urea synthesis (d), and cytochrome P450 expression (e) of HepG2 after coculture with 3T3, ECs, and both 3T3 and ECs in the liver-on-a-chip system for 7 days; ∗∗∗p < 0.01.
