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Polyphyllin I block cell cycle at G0/G1 phase in a dose-dependent manner. PC3 and DU145 cells were treated with 2 different concentrations of Polyphyllin I (0.5 and 1.0 μg/mL, respectively) and cell cycle was analyzed using flow cytometry. (A and B) Cell cycle distribution of PC3 and DU145 cells, respectively.
