Figure 2.

Serial clinical features of the patient at different time points. (A) Enteroscopic images at different time points: pre-fecal microbiota transplantation (FMT): mucosal exfloliation, erosions, congestion and swelling in the small intestine, colon and rectum; after the 4th FMT treatment: signs of disease resolution with nearly normal mucosal surface of the ileocecal, ascending colon, and rectum; and 6-month following discharge from the hospital: complete recovery of mucosal surface. (B) Histopathological examination of ascending colon: mucosal erosion, decreased numbers of goblet cells, increased numbers of lymphocytes, and small amounts of eosinophils in the lamina propria, as well as diffuse eosinophilic infiltration can be observed. (C) Histopathological examination of colon mucosa under a transmission electronic microscope: epithelial cell damage, enlarged gap between cells, shortened microvillus, and disordered crypt structure can be seen.