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Hazard ratio for device- or procedure-related serious adverse event with annular closure device vs. controls by baseline patient characteristics. ACD = annular closure device; BMI = body mass index; ODI = Oswestry Disability Index. Plotted values are hazard ratio and 95% confidence interval. Hazard ratio < 1 indicates lower risk with ACD; > 1 indicates higher risk with ACD. Continuous variables are categorized by the median value.
