Table 3. Significant variants associated with hypertriglyceridemia (TG ≥150 mg/dL).

Chr	SNP	Position	Gene	M	Discovery set			Replication set
					MAF	OR	P	MAF	OR	P
					(case / control)	(95% CI)		(case / control)	(95% CI)
2	rs780092	27743154	GCKR	G	0.275 / 0.334	0.752	4.82×10−9	0.279 / 0.336	0.753	1.19×10−3
						(0.683–0.827)			(0.635–0.894)
2	rs780093	27742603	GCKR	C	0.395 / 0.471	0.730	2.55×10−12	0.398 / 0.474	0.721	5.47×10−5
						(0.669–0.797)			(0.615–0.845)
2	rs780094	27741237	GCKR	C	0.397 / 0.472	0.736	6.49×10−12	0.400 / 0.475	0.723	5.91×10−5
						(0.674–0.803)			(0.617–0.847)
2	rs1260326	27730940	GCKR	C	0.385 / 0.460	0.731	3.89×10−12	0.392 / 0.463	0.729	1.07×10−4
						(0.669–0.799)			(0.622–0.856)
2	rs1260333	27748624	GCKR	G	0.392 / 0.468	0.734	5.20×10−12	0.392 / 0.472	0.704	1.75×10−5
						(0.672–0.802)			(0.600–0.827)
2	rs1919127	27801493	C2orf16	T	0.417 / 0.477	0.776	1.18×10−8	0.420 / 0.491	0.755	3.67×10−4
						(0.711–0.846)			(0.646–0.881)
2	rs1919128	27801759	C2orf16	A	0.415 / 0.476	0.772	7.39×10−9	0.419 / 0.491	0.754	3.65×10−4
						(0.707–0.843)			(0.646–0.881)
11	rs662799	116663707	APOA5	G	0.391 / 0.278	1.770	4.97×10−34	0.389 / 0.277	1.732	8.49×10−11
						(1.614–1.94)			(1.467–2.045)
11	rs2075291	116661392	APOA5	A	0.117 / 0.068	1.940	3.67×10−19	0.106 / 0.069	1.739	6.93×10−5
						(1.678–2.243)			(1.324–2.284)
11	rs2266788	116660686	APOA5	G	0.273 / 0.209	1.482	9.26×10−15	0.281 / 0.207	1.538	4.03×10−6
						(1.342–1.637)			(1.281–1.846)
11	rs603446	116654435	ZPR1	T	0.191 / 0.242	0.726	6.24×10−9	0.178 / 0.231	0.705	5.48×10−4
						(0.651–0.809)			(0.578–0.860)
11	rs964184	116648917	ZPR1	G	0.271 / 0.208	1.479	1.47×10−14	0.279 / 0.205	1.552	2.93×10−6
						(1.339–1.634)			(1.291–1.866)
11	rs2075295	116628401	BUD13	C	0.404 / 0.466	0.755	4.56×10−10	0.424 / 0.480	0.793	4.04×10−3
						(0.691–0.825)			(0.677–0.929)
11	rs11216126	116617240	BUD13	C	0.150 / 0.205	0.666	1.34×10−11	0.177 / 0.206	0.808	3.70×10−2
						(0.592–0.749)			(0.661–0.987)
11	rs1558861	116607437	BUD13	C	0.275 / 0.213	1.463	5.85×10−14	0.278 / 0.212	1.463	4.37×10−5
						(1.325–1.616)			(1.219–1.756)

Chr, chromosome; rs number, SNP ID in dbSNP database; M, minor allele; MAF, minor allele frequency; OR, odds ratio; CI, confidence interval, respectively