Table 2.

Biological Findings of Study Participants According to Groups

Patient Characteristics	Type 2 Diabetes n =54 M[Q1-Q3]	Obese n =54 M[Q1-Q3]	Lean n =54 M[Q1-Q3]	p-value
FBG (g/L)	1.07[1.02–1.39]	1.05[1.03–1.09]	1.01[0.97–1.06]	0.012
HbA1c (%)	6.05[4.93–6.98]	5.94[4.80–6.50]	5.1[4.60–5.39]	0.06
LDL cholesterol (g/L)	0.98[0.83–1.09]	0.93[0.85–1.05]	0.88[0.74–1.03]	0.007
HDL-Cholesterol (g/L)	0.40[0.38–0.46]	0.43[0.38–0.49]	0.53[0.44–0.57]	0.68
Total cholesterol (g/L)	1.73[1.58–1.85]	1.74[1.62–1.85]	1.67[1.54–1.80]	0.01
Triglycerides (g/L)	1.78[1.45–2.01]	1.65[1.43–1.92]	1.58[1.32–1.47]	0.018
hs-CRP (mg/dL)	1.36[0.22–3.01]	1.81[0.57–4.42]	0.27[0.20–0.66]	0.002

Notes: Boldface type indicates statistical significance where p< 0.05. Patients with obesity and type 2 diabetes had significantly higher levels of PCSK9, hs-CRP, triglycerides, total cholesterol and fasting glycaemia than the lean group.

Abbreviations: M[Q1–Q3], Median [25th–75th percentile]; FPG, Fasting Plasma Glucose; HbA1c, Glycated hemoglobin; HDL, high-density lipoprotein; LDL, low-density lipoprotein; hs-CRP, High sensitive C-reactive protein.