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. 2020 Jan 7;3:3. doi: 10.1038/s42003-019-0729-3

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© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 6 — a Single channel data from ref. ³¹ with noise approximately 850,000 data points decimated by a factor of 50 for display only. b The modal idealisation by five ion channel experts (“golden” idealisation). c Agreement clustering and heatmap between “golden” dataset, MDL, Deep-Channel and SKM. d A zoomed view of 500 ms of raw biological data taken from (a). e The expert consensus (modal) idealisation. f The idealisation output by SKM (after setting channel closed and open levels and setting the number of channels to 1), g By Deep-Channel and h by MDL. Note that c, f, g and h were produced without baseline correction.