Table 3.

Ranking of models (sets of risk factors) for age-related macular degeneration (AMD) according to their posterior probability (PP) after exclusion of outlying and influential variants ($n=145$).

	Models or sets of risk factor(s)	Posterior probability (PP)	Model-specific causal estimates ${\widehat{\theta }}_{\gamma }$
1	XL.HDL.C	0.156	0.509
2	L.HDL.C	0.078	0.384
3	XL.HDL.C,XS.VLDL.TG	0.026	0.457,−0.181
4	IDL.TG,XL.HDL.C	0.025	−0.179,0.495
5	HDL.D	0.023	0.359
6	Serum.C,XL.HDL.C	0.019	−0.183,0.573
7	S.VLDL.TG,XL.HDL.C	0.015	−0.172,0.443
8	S.VLDL.C,XL.HDL.C	0.014	−0.164,0.477
9	Serum.TG,XL.HDL.C	0.014	−0.169,0.465
10	S.HDL.TG,XL.HDL.C	0.013	−0.18,0.415

Results are given after excluding genetic variants in the APOE, FUTC, and LIPC regions. ${\widehat{\theta }}_{\gamma }$ is the causal effect estimate for a specific model

HDL.D HDL diameter, IDL.TG triglycerides in IDL, L.HDL.C total cholesterol in large HDL, LDL.D LDL diameter, Serum.C serum total cholesterol, Serum.TG serum total triglycerides, S.VLDL.C total cholesterol in small VLDL, S.VLDL.TG triglycerides in small VLDL, XS.VLDL.TG triglycerides in very small VLDL, XL.HDL.C total cholesterol in very large HDL