Table 1.

Comparison of the analytical performance of the strep-B-QDs-GO-CTAB-AuNP aptamer-based fluorescence nanoprobe with other published aptamer-based fluorescence nanoprobe for cocaine

Strategy	Method	LOD	Detection time	Ref.
FRET aptamer assay	Fluorescence turn-OFF	10 μM	–	[37]
Structure-switching aptamers-SYBR Gold-exonuclease I	Fluorescence turn-ON	5 μM	25 min	[7]
2-amino-5,6,7-trimethyl-1,8-naphthyridine aptamer assay	Fluorescence turn-ON	200 nM	20 s	[1]
QDs-FRET aptamer assay	Fluorescence turn-OFF and turn-ON	0.5 μM	1 min 40 s	[8]
Strand displacement amplification aptamer assay	Fluorescence turn-ON	1 nM	2 h	[38]
G-Quadruplex-Iridium (III) complex aptamer assay	Fluorescence turn-ON	30 nM	30 min	[4]
2-Amino-5,6,7-trimethyl-1,8- naphthyridine-SYBR Green I aptamer assay	Fluorescence turn-ON	56 nM	20 s	[39]
GO and exonuclease III-assisted signal amplification	Fluorescence turn-ON	0.1 nM	17 min	[9]
Strep-B-QDs-GO-CTAB-AuNP aptamer assay	Fluorescence turn-ON	4.6 nM	~ 2 min	This work