Table 1.
Compartments created in the CellDesigner platform in line with the structure and function of the outer retina.
| Outer retina anatomical compartments | Substructures within anatomical compartments | Further subclassification of anatomical structures and organelles | Organelles and deposits in anatomical substructures |
|---|---|---|---|
| Choroid | Choriocapillaris | Lumen | Macrophage |
| Choriocapillaris | Endothelium | Mitochondria | |
| Bruch’s membrane | Outer collagen free zone | ||
| Outer collagenous layer | |||
| Elastin layer | |||
| Inner collagenous layer | |||
| Inner collagen free zone | Hard drusen | ||
| Soft drusen/basal linear deposit | |||
| RPE | RPE basement membrane | Basal laminar deposit | |
| Exosome | |||
| RPE | Nucleus | ||
| Endoplasmic reticulum | |||
| Golgi | |||
| Mitochondria | |||
| Endocytic vesicle | |||
| Transcytotic vesicle | |||
| Transport vesicle | |||
| Early endosome | |||
| Recycling endosome | |||
| Late endosome | |||
| Lysosome | |||
| Phagosome | |||
| Phagolysosome | |||
| Autophagosome | |||
| Melanosome | |||
| Secretory vesicle | |||
| Interphotoreceptor Matrix | Reticular subretinal drusenoid deposit | ||
| Macrophage | |||
| Photoreceptor | Rod outer segment | Disks | |
| Shed rod outer segment | Disks | ||
| Cilium | |||
| Rod inner segment | Endocytic vesicle | ||
| Mitochondria | |||
| Endoplasmic reticulum | |||
| Nucleus |