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. Author manuscript; available in PMC: 2021 Feb 1.
Published in final edited form as: Mol Carcinog. 2019 Nov 29;59(2):193–201. doi: 10.1002/mc.23140

Fig. 6. Gartanin induces autophagy.

Fig. 6.

A. PC3-LC3-eGFP cells were treated with 0.1% DMSO or indicated concentrations of Gartanin for 24 hours, and then observed under a fluorescence microscope. B. Quantitative analysis of cells with the punctate staining of LC3B after 24 hours of treatment with indicated concentrations of Gartanin compared with 0.1% DMSO treatment. “**” represents P < 0.01. C. 22Rv1 cells and PC3 cells were treated with indicated concentrations of Gartanin for 24 hours and LC3B antibody were used to detect LC3 cleavage. D. Proposed mechanisms of Gartanin’s action as a novel NEDDylation inhibitor.