Table 2.
Logistic analysis and diagnostic performance of miRNAs in patients with HCC compared with HBV group
MicroRNA group | AUC | Univariate | Multivariate | ||
---|---|---|---|---|---|
| |||||
P value | HR | 95% CI | P value | ||
AFP at diagnosis | 0.712 | 0.002 | 1.152 | 0.962-1.457 | 0.743 |
ALT (U/L) | 0.689 | 0.012 | 1.021 | 0.583-1.522 | 0.552 |
Liver cirrhosis | 0.677 | 0.023 | 0.788 | 0.367-1.263 | 0.156 |
miRNA-26a | 0.922 | 0.001 | 0.134 | 0.024-0.241 | 0.001 |
miRNA-29c | 0.934 | 0.001 | 0.104 | 0.016-0.832 | 0.004 |
miRNA-21 | 0.935 | 0.001 | 0.084 | 0.027-0.932 | 0.012 |
Abbreviations: CI, confidence interval; AUC, area under the receiver operating characteristic curve; HCC, hepatocellular carcinoma.