miR-106a regulated migration, invasion, and radiosensitivity of HCC cells by targeting FBXW7. A-D. Cell migration and invasion were measured in SMMC-7721 and HepG2 cells transfected with anti-miR-NC, anti-miR-106a, anti-miR-106a+si-NC or anti-miR-106a+si-FBXW7 by trans-well assay. E and F. The survival fraction was analyzed in SMMC-7721 and HepG2 cells transfected with anti-miR-NC, anti-miR-106a, anti-miR-106a+si-NC or anti-miR-106a+si-FBXW7 after various doses of irradiation for 24 h by colony formation. G and H. The abundance of γ-H2AX was examined in SMMC-7721 and HepG2 cells transfected with anti-miR-NC, anti-miR-106a, anti-miR-106a+si-NC, or anti-miR-106a+si-FBXW7 after 6 Gy irradiation for different times by western blot. *P<0.05, **P<0.01.