Table 2.
KEGG analysis classification and the enrichment result
| Pathway Name | Match Status | P | -log (p) | Holm p | FDR | Impact |
|---|---|---|---|---|---|---|
| Citrate cycle (TCA cycle) | 5/20 | 9.5363E-8 | 16.166 | 7.6291E-6 | 7.6291E-6* | 0.1911 |
| Glycolysis or Gluconeogenesis | 4/31 | 3.6833E-5 | 10.209 | 0.0029098 | 0.0014733* | 0.1035 |
| Glyoxylate and dicarboxylate metabolism | 4/50 | 2.4973E-4 | 8.2951 | 0.019479 | 0.0066594* | 0.03137 |
| Pyruvate metabolism | 3/32 | 0.0010634 | 6.8463 | 0.081884 | 0.021269* | 0.13756 |
| Galactose metabolism | 3/41 | 0.0022033 | 6.1178 | 0.16745 | 0.035253* | 0.03469 |
| Pentose phosphate pathway | 2/32 | 0.018298 | 4.001 | 1.0 | 0.24397 | 0.08639 |
| Propanoate metabolism | 2/35 | 0.021697 | 3.8306 | 1.0 | 0.24796 | 0.00134 |
| Glycerophospholipid metabolism | 2/39 | 0.026606 | 3.6266 | 1.0 | 0.26606 | 0.07129 |
| Nicotinate and nicotinamide metabolism | 2/44 | 0.033318 | 3.4017 | 1.0 | 0.29616 | 0.0015 |
| Purine metabolism | 2/92 | 0.12264 | 2.0985 | 1.0 | 0.98112 | 0.01643 |
| Alanine, aspartate and glutamate metabolism | 1/24 | 0.14857 | 1.9067 | 1.0 | 1.0 | 0.0 |
| Sphingolipid metabolism | 1/25 | 0.15429 | 1.8689 | 1.0 | 1.0 | 0.01288 |
| Phenylalanine, tyrosine and tryptophan biosynthesis | 1/27 | 0.16561 | 1.7981 | 1.0 | 1.0 | 0.0 |
| Glycerolipid metabolism | 1/32 | 0.19331 | 1.6435 | 1.0 | 1.0 | 0.0 |
| Inositol phosphate metabolism | 1/39 | 0.23064 | 1.4669 | 1.0 | 1.0 | 0.01203 |
| Butanoate metabolism | 1/40 | 0.23583 | 1.4446 | 1.0 | 1.0 | 0.01774 |
| Phenylalanine metabolism | 1/45 | 0.26134 | 1.3419 | 1.0 | 1.0 | 0.0 |
| Fructose and mannose metabolism | 1/48 | 0.27625 | 1.2864 | 1.0 | 1.0 | 0.04115 |
| Starch and sucrose metabolism | 1/50 | 0.28604 | 1.2516 | 1.0 | 1.0 | 0.01703 |
| Pentose and glucuronate interconversions | 1/53 | 0.30049 | 1.2024 | 1.0 | 1.0 | 0.0 |
Match Status = Hit/Total. The Total is the total number of compounds in the pathway; the Hits is the actually matched number. The table below shows the detailed. The P is the original p value calculated from the enrichment analysis; the Holm p is the p value adjusted by Holm-Bonferroni method; the FDR p is the p value adjusted using False Discovery Rate results from the pathway analysis.
*
FDR<0.05.