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. 2019 Nov 21;10(12):955. doi: 10.3390/genes10120955

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© 2019 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Effect of genistein on global DNA methylation in HeLa cells. Genistein (50 µM) significantly decrease the levels of global DNA methylation in HeLa cells in a time dependent manner. The decrease is methylation level is represented as a percentage of the untreated control. Values are means ± SD of three independent experiments (*p ≤ 0.05).