Figure 5.
Effect of genistein on 5´ CpG island promoter methylation of tumour suppressor genes (TSGs) in HeLa cells using Human Tumor Suppressor Genes EpiTect Methyl II Signature PCR Array. Genistein (50 µM) significantly decreased the promoter methylation levels in HeLa cells in comparison with the untreated control. The values are mean ± SD of three independent experiments (*p ≤ 0.05).