Table 2.
Topological parameters of target gene set.
| S.No. | Gene Name | Degree | Betweenness | Expression |
|---|---|---|---|---|
| 1. | TP53 | 21 | 321.87 | 1.78 |
| 2. | HDAC1 | 19 | 197.1 | 0.46 |
| 3. | DNMT1 | 9 | 70.1 | 0.31 |
| 4. | CDKN1A | 8 | 50.55 | 0.5 |
| 5. | SUV39H1 | 7 | 40.5 | 0.5 |
| 6. | CDK2 | 7 | 39.98 | 0.45 |
| 7. | KDM1A | 7 | 22.08 | 0.4 |
| 8. | MAPK3 | 5 | 74.08 | 0.4 |
| 9. | AKT1 | 5 | 44.48 | 0.45 |
| 10. | CCNB1 | 5 | 33.13 | 0.31 |
| 11. | DNMT3B | 5 | 2.2 | 0.33 |
| 12. | TP73 | 5 | 1.42 | 5.27 |
| 13. | HDAC5 | 4 | 10.24 | 0.46 |
| 14. | AURKA | 4 | 7.32 | 0.4 |
| 15. | MTA1 | 4 | 0 | 0.5 |
| 16. | DNMT3A | 4 | 0 | 0.5 |
| 17. | CIITA | 3 | 10.53 | 4.93 |
| 18. | TWIST1 | 3 | 2.95 | 0.5 |
| 19. | HDAC6 | 3 | 1.42 | 0.5 |
| 20. | ESCO2 | 3 | 1.07 | 13.93 |
| 21. | MAP2K1 | 2 | 7.39 | 0.47 |
| 22. | PTEN | 2 | 7.06 | 2.1 |
| 23. | TERT | 2 | 7.06 | 0.5 |
| 24. | PAK1 | 2 | 4.78 | 0.5 |
| 25. | FOXO1 | 2 | 4.47 | 1.89 |
| 26. | CDH1 | 2 | 2.23 | 2.76 |
| 27. | AURKB | 2 | 0 | 0.44 |
| 28. | CCNB2 | 2 | 0 | 0.5 |
| 29. | SETD7 | 2 | 0 | 2.35 |
| 30. | CCND3 | 2 | 0 | 0.5 |
| 31. | FOS | 2 | 0 | 0.37 |
| 32. | DAPK1 | 2 | 0 | 3.49 |
| 33. | UBE2A | 2 | 0 | 0.38 |
| 34. | TP53I3 | 1 | 0 | 4.96 |
| 35. | RUNX3 | 1 | 0 | 3.76 |
| 36. | SOCS1 | 1 | 0 | 10.62 |
| 37. | PTPRR | 1 | 0 | 4.03 |
| 38. | KDM5C | 1 | 0 | 0.5 |