Table 2.

Area under the curve of admission high-sensitivity C reactive protein (hs-CRP) added to serum creatinine (sCr) and to the clinical variables found to be independently associated with acute kidney injury, for the prediction of the primary endpoint (acute kidney injury), and reclassification statistics comparisons.

	AUC (95% CI)	p Value AUC	p Value for AUC Comparison	NRI (95% CI)	p Value NRI
Admission sCr	0.66 (0.62–0.70)	<0.001	-	-	-
Admission hs-CRP + sCr	0.72 (0.68–0.76)	<0.001	<0.001	14% (10–17)	0.01
Clinical predictors *	0.79 (0.77–0.83)	<0.001	-	-	-
Admission hs-CRP + clinical predictors *	0.81 (0.78–0.84)	<0.001	0.002	8% (3–12)	<0.001

AUC—area under the curve; CI—confidence intervals; NRI—net reclassification improvement. *Age, admission serum creatinine, left ventricular ejection fraction, admission glycemia, and acute myocardial infarction type.