Table 3.
Association of S. aureus toxin genes with methicillin susceptibility or resistance.
|
S. aureus Total = 77 |
MSSA Total = 49 |
MRSA Total = 28 |
OR * | P † | ||||
|---|---|---|---|---|---|---|---|---|
| Toxin | N | % | N | % | N | % | ||
| sea | 25 | 32.5% | 17 | 34.7% | 8 | 28.6% | 0.76 | 0.62 |
| seb | 3 | 3.9% | 3 | 6.1% | 0 | 0.0% | - | 0.30 |
| sec | 5 | 6.5% | 5 | 10.2% | 0 | 0.0% | - | 0.15 |
| sed | 8 | 10.4% | 3 | 6.1% | 5 | 17.9% | 3.28 | 0.13 |
| see | 5 | 6.5% | 4 | 8.2% | 1 | 3.6% | 0.42 | 0.65 |
| seg | 69 | 89.6% | 45 | 91.8% | 24 | 85.7% | 0.54 | 0.45 |
| sel-h | 0 | 0.0% | 0 | 0.0% | 0 | 0.0% | - | - |
| sel-i | 69 | 89.6% | 44 | 89.8% | 25 | 89.3% | 0.95 | 1.00 |
| sel-k | 5 | 6.5% | 3 | 6.1% | 2 | 7.1% | 1.18 | 1.00 |
| sel-l | 3 | 3.9% | 3 | 6.1% | 0 | 0.0% | - | 0.30 |
| sel-m | 67 | 87.0% | 42 | 85.7% | 25 | 89.3% | 1.38 | 0.74 |
| sel-n | 68 | 88.3% | 43 | 87.8% | 25 | 89.3% | 1.16 | 1.00 |
| sel-o | 71 | 92.2% | 46 | 93.9% | 25 | 89.3% | 0.55 | 0.66 |
| sel-p | 46 | 59.7% | 34 | 69.4% | 12 | 42.9% | 0.34 | 0.03 |
| sel-q | 17 | 22.1% | 11 | 22.4% | 6 | 21.4% | 0.94 | 1.00 |
| sel-u | 69 | 89.6% | 45 | 91.8% | 24 | 85.7% | 0.54 | 0.45 |
| sel-x | 61 | 79.2% | 33 | 67.3% | 28 | 100.0% | - | 0.0003 |
| tstH | 9 | 11.7% | 9 | 18.4% | 0 | 0.0% | - | 0.02 |
| hla | 63 | 81.8% | 37 | 75.5% | 26 | 92.9% | 4.15 | 0.07 |
| hlb | 41 | 53.2% | 19 | 38.8% | 22 | 78.6% | 5.65 | 0.001 |
* OR = Odds ratio, values > 1 indicate increased odds of the toxin being encoded in MRSA versus methicillin-susceptible S. aureus (MSSA). †P values calculated by Fisher’s exact test. Bold font indicates genes belonging to the enterotoxin gene cluster.