Table 2.

Outcome after pallidal deep brain stimulation of individuals with DYT-THAP1 dystonia.

Patient Number	Age at GPi-DBS (Years)	Disease Duration Before GPi-DBS (Years)	Length of Follow-Up after GPi-DBS (Years, Months)	Change in BFM-M, Last Follow-Up Compared to Baseline (%)	Responder (>25% Improvement BFM-M)	Effect on Speech and/or Swallowing	Intra-Cerebral Revision (number)	DBS Device at Last Follow-Up (Number of Changes)	Stimulation Frequency at Last Follow-Up (Hz)
1	57	15	1 year 8 months	−13	no	no	0	Medtronic Activa RC (1)	130
2	14	5	1 year 2 months	−37	yes	some	0	Medtronic Activa PC	130
3	13	7	11 years 1 month	−21	initially	some	0	Medtronic Activa RC (2)	130
4	17	2	10 years 0 month	−57	yes	no	0	Activa RC (2)	180
5	14	8	8 years 7 months	−29	yes	no	0	Medtronic Activa RC (1)	180
6	32	18	7 months	−68	yes	no	0	Medtronic Activa SC	100
7	26	19	13 years 9 months	−78	yes	no	0	Medtronic Activa SC (1)	RGPi 110; LGPi 90
8	54	14	3 years 7 months	−61	yes	no	0	Medtronic Activa SC	RGPi 125; LGPi 90
9	11	5	6 years 0 month	−62	yes	no	0	Medtronic Activa RC	130
10	22	13	1 year 0 month	−74	yes	no	0	Soletra, medtronic leads	130
11	20	11	16 years 4 months	−60	yes	no	1	Medtronic Activa RC	130
12	12	8	6 years 11 months	−46	yes	some	0	Activa RC (1)	130
13	8	2	1 year 1 month	−20	no	some	2	Medtronic Activa RC (1)	NR
14	19	10	1 year 0 month	−58	yes	no	0	Vercise-DBS-system/Boston Scientific	130

GPi-DBS = pallidal deep brain stimulation; BFM-M = Burke Fahn Marsden Dystonia Rating Scale—movement subscore; DBS = deep brain stimulation; RGPi = right globus pallidus interna; LGPi = left globus pallidus interna; (x) = number of changes of DBS device; NR = not reported.