Table 1.
Clinical, angiographic, and procedural details of the 100 one-stop-management patients.
| All, n = 230 | LVO, n = 166 | SVO, n = 25 | ICH, n = 24 | Todd’s, n = 11 | RLVO, n = 4 | |
|---|---|---|---|---|---|---|
| Age, median (IQR) | 78 (69–84) | 77 (68–84) | 79 (71–87) | 78 (75–83) | 79 (73–82) | 81 (77–86) |
| Admission NIHSS | 15 (12–19) | 16 (13–19) | 13 (11–15) | 15 (10–17) | 12 (11–15) | 13 (11–13) |
| Female | 123 (54%) | 90 (54%) | 12 (48%) | 12 (50%) | 5 (46%) | 4 (100%) |
| IV–rtPA | 144 (63%) | 112 (68%) | 23 (92%) | 1 | 4 (36%) | 4 (100%) |
| Hemorrhage on initial FDCT | 25 (11%) | 1 (1%) | 0 (0%) | 24 (100%) | 0 (0%) | 0 (0%) |
| Occlusion site | ||||||
| ICA-T | 41 (25%) | |||||
| M1 | 88 (53%) | |||||
| M2 | 15 (9%) | |||||
| Other | 22 (13%) | |||||
| Tandem occlusion | 34 (21%) | |||||
|
Times, min
(IQR; 90th Percentile) |
||||||
| Symptom to door | 130 (70–195; 253) | 154 (67–205; 264) | 82 (66–134; 205) | 105 (69–129; 204) | 131(95–146; 186) | 229 (181–259) |
| Door to FDCT | 15 (10–20; 26) | 14 (9–19; 25) | 16 (12–24; 32) | 17 (14–22; 30) | 21 (13–23; 31) | 16 (14–16) |
| Door to IV–rtPA | 22 (20–30; 41) | 22 (20–29; 38) | 26 (20–45; 53) | |||
| Door to treatment startα | 21 (18–33; 34) | 27 (19–32; 37) | ||||
| Door to groin | 29 (22–39; 50) | |||||
| Groin to reperfusion | 40 (28–60; 80) | |||||
| FDCT to reperfusion | 59 (45–82; 101) | |||||
| Door to reperfusion | 72 (58–91; 117) | |||||
| Door to reperfusion M1 | 64 (56–87; 102) | |||||
| extCT to FDCT | 124 (110–155; 218) | |||||
| Direct admission | 127 (55%) | 74 (45%) | 19 (76%) | 23 (96%) | 11 (100%) | 0 (0%) |
| Working hoursβ | 95 (41%) | 68 (41%) | 13 (52%) | 11 (46%) | 2 (18%) | 1 (25%) |
| Reperfusion, mTICI2b-3 | 142 (86%) | |||||
| Any hemorrhage on FU | 49 (21%) | 25 (15%) | 0 (0%) | 24 (100%) | 0 (0%) | |
| PH-2 hematoma on FU | 2 (1%) | |||||
| sICH | 6 (4%) | |||||
| Discharge NIHSS | 5 (2–10) | 5 (2–12) | 7 (4–10) | 5 (1–9) | 4 (1–6) | 6 (4–7) |
| Discharge mRS | 4 (1–5) | 4 (1–5) | 4 (2–5) | 2 (2–6) | 3 (1–4) | 3 (3–4) |
| Mortality | 45/230 (20%) | 36 (22%) | 2 (8%) | 5 (30%) | 2 (18%) | 0 (0%) |
| 90 d mRS | 4 (1–6) | |||||
| 90 d favorable outcome | 54/147 (37%) |
LVO, large vessel occlusion; SVO, small vessel occlusion; ICH, intracranial hemorrhage; RLVO, recanalized LVO during transfer; IQR, interquartile range, NIHSS, National Institutes of Health Stroke Scale; IV-rtPA, intravenous recombinant tissue plasminogen activator; FDCT, flat-detector CT; extCT, external CT in primary stroke center; mTICI, modified thrombolysis in cerebral infarction score; FU, follow-up; mRS, modified Rankin scale; α, intravenous injection of antihypertensive drugs in case of ICB or sedative drugs in case of seizures; β, weekdays 08:00 to 17:00.