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. 2019 Dec 9;8(12):2172. doi: 10.3390/jcm8122172

Table 3.

Bivariate and multivariate logistic regression analysis: odds for FNA.

Bivariate Multivariate
Independent Variables OR 95% CI p OR 95% CI p
Age (years) 0.991 0.984–0.998 0.009 0.988 0.975–1.001 0.062
Sex 0.716 0.071
 Male 1 (ref.) 1 (ref.)
 Female 1.053 0.797–1.393 1.534 0.964–2.440
Nodule size (mm) 1.236 1.210–1.263 <0.001 - - -
Nodule size (mm) <0.001 <0.001
 <20 1 (ref.) 1 (ref.)
 ≥20–<40 9.13 6.774–12.305 <0.001 10.97 6.108–19.702 <0.001
 ≥40 16.501 8.100–33.614 <0.001 34.476 4.734–251.073 <0.001
Echogenicity <0.001 0.002
 Hyperechoic 1 (ref.) 1 (ref.)
 Isoechoic 3.615 2.089–6.256 <0.001 2.385 1.233–4.614 0.010
 Hypoechoic 1.234 0.772–1.973 0.38 1.14 0.643–2.021 0.654
Composition 0.002 - - -
 Mixed cystic and solid 1(ref.)
 Solid 0.677 0.525–0.872
Margins 0.252 - - -
 Regular 1 (ref.)
 Irregular 1.452 0.767–2.751
Microcalcifications <0.001 0.001
 Absent 1 (ref.) 1 (ref.)
 Present 5.505 2.418–12.532 10.931 2.607–45.829

FNA: fine-needle aspiration; OR: odds ratio.