Table 4.
Bivariate and multivariate logistic regression analysis: odds of Bethesda IV-V-VI.
| Bivariate | Multivariate | |||||
|---|---|---|---|---|---|---|
| Independent Variables | OR | 95% CI | p | OR | 95% CI | p |
| Age (years) | 0.992 | 0.980–1.002 | 0.158 | 0.992 | 0.977–1.007 | 0.283 |
| Sex | 0.124 | 0.151 | ||||
| Male | 1 (ref.) | 1 (ref.) | ||||
| Female | 0.714 | 0.465–1.096 | 0.64 | 0.348–1.177 | ||
| Nodule size (mm) | 1.01 | 0.998–1.023 | 0.09 | - | - | - |
| Nodule size (mm) | 0.45 | - | - | - | ||
| <20 | 1 (ref.) | |||||
| ≥20–<40 | 1.22 | 0.883–1.685 | 0.227 | |||
| ≥40 | 1.218 | 0.759–1.955 | 0.414 | |||
| Echogenicity | 0.394 | - | - | - | ||
| Hyperechoic | 1 (ref.) | |||||
| Isoechoic | 0.92 | 0.390–2.171 | 0.849 | |||
| Hypoechoic | 1.25 | 0.549–2.847 | 0.568 | |||
| Composition | <0.001 | 0.004 | ||||
| Mixed cystic and solid | 1 (ref.) | 1 (ref.) | ||||
| Solid | 2.625 | 1.621–4.251 | 2.217 | 1.297–3.791 | ||
| Margins | 0.001 | 0.021 | ||||
| Regular | 1 (ref.) | 1 (ref.) | ||||
| Irregular | 2.712 | 1.477–4.980 | 2.592 | 1.156–5.813 | ||
| Microcalcifications | <0.001 | 0.006 | ||||
| Absent | 1 (ref.) | 1 (ref.) | ||||
| Present | 2.976 | 1.906–4.648 | 2.256 | 1.262–4.033 | ||
OR: odds ratio.